非结核分枝杆菌病分子诊断技术概述

doi:10.3969/j.issn.2096-8493.2021.02.002

摘要/Abstract

摘要：

近年来,非结核分枝杆菌(nontuberculous mycobacteria,NTM)病患者例数呈快速增多趋势。NTM病主要依靠实验室病原学检测进行诊断。随着NTM病的增多,人们对其危害性越来越重视,很多分子诊断技术应用于临床。作者概述了常见NTM检测及鉴定的分子诊断技术,并分析其技术特点,希望能为医务工作者选择合适的技术提供帮助。

关键词: 分枝杆菌,非典型性, 分子诊断技术, 鉴别

Abstract:

Recently human infections caused by nontuberculous mycobacteria (NTM) are increasing. NTM diseases are mainly diagnosed by laboratory bacteriological assays. As a result of an increasing emphasis on the importance of differential identification of NTM species, several molecular tools have recently been introduced in clinical settings. In this paper, we summarized frequently used molecular diagnostics for identification and differentiation of NTM species and their relevant strengths and weaknesses to facilitate the choice of related assays.

Key words: Mycobacteria, atypical, Molecular diagnostic techniques, Species identification

廖鑫磊, 王桂荣. 非结核分枝杆菌病分子诊断技术概述[J]. 结核与肺部疾病杂志, 2021, 2(2): 98-101. doi: 10.3969/j.issn.2096-8493.2021.02.002

LIAO Xin-lei, WANG Gui-rong. Recent advances in molecular diagnostics of nontuberculous mycobacterial diseases[J]. Journal of Tuberculosis and Lung Disease, 2021, 2(2): 98-101. doi: 10.3969/j.issn.2096-8493.2021.02.002

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