慢性阻塞性肺疾病合并支气管扩张症的研究进展

doi:10.19983/j.issn.2096-8493.20230093

摘要/Abstract

摘要：

慢性阻塞性肺疾病(COPD)是一种异质性肺部状态,是常见的慢性呼吸系统疾病之一,患病率与病死率均较高。支气管扩张症是由各种病因引起的反复发生的化脓性感染,导致中小支气管反复损伤和(或)阻塞,致使支气管壁结构破坏,引起支气管异常和持久性扩张。支气管扩张症和COPD同时存在于同一患者的重叠综合征,即为支气管扩张症-慢性阻塞性肺疾病重叠综合征(BCOS)。BCOS是一种临床上常见的综合征,但有关BCOS临床特征及预后的研究很少。笔者通过大量文献检索分析,对COPD合并支气管扩张症的最新机制研究、临床特征研究及相关风险和预后研究进展进行全面阐述,旨在更清晰地认识这一综合征,并为BCOS的临床防治提供新的思路。

关键词: 肺疾病, 慢性阻塞性, 支气管扩张症, 综述文献(主题)

Abstract:

Chronic obstructive pulmonary disease (COPD) is a heterogeneous pulmonary condition and a common chronic respiratory disease with high morbidity and mortality. Bronchiectasis is a recurring pyogenic infection caused by various causes, resulting in repeated damage and/or obstruction of the small and medium bronchus, the destruction of the bronchial wall structure, bronchial abnormalities and persistent dilation. Bronchodilatation-chronic obstructive pulmonary disease overlap syndrome (BCOS) is a combination of bronchiectasis and COPD in the same patient. BCOS is a common clinical syndrome, but there are few studies on the clinical characteristics and prognosis of BCOS. Through a large number of literature retrieval and analysis, this review comprehensively expounds the latest mechanism research, clinical characteristics research, and related risk and prognosis research progress of COPD complicated with bronchiectasis, aiming at a clearer understanding of this syndrome and providing new ideas for clinical prevention and treatment of BCOS.

Key words: Pulmonary disease, chronic obstructive, Bronchiectasis, Review literature as topic

中图分类号:

戴中上, 钟严俊, 陈燕. 慢性阻塞性肺疾病合并支气管扩张症的研究进展[J]. 结核与肺部疾病杂志, 2023, 4(6): 499-505. doi: 10.19983/j.issn.2096-8493.20230093

Dai Zhongshang, Zhong Yanjun, Chen Yan. Research progress on chronic obstructive pulmonary disease with bronchiectasis[J]. Journal of Tuberculosis and Lung Disease, 2023, 4(6): 499-505. doi: 10.19983/j.issn.2096-8493.20230093

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