结核与肺部疾病杂志 ›› 2023, Vol. 4 ›› Issue (2): 153-157.doi: 10.19983/j.issn.2096-8493.20230021
收稿日期:
2023-01-16
出版日期:
2023-04-20
发布日期:
2023-04-07
通信作者:
赵海金,Email:基金资助:
Huang Junwen, Chen Ying, Cai Shaoxi, Zhao Haijin()
Received:
2023-01-16
Online:
2023-04-20
Published:
2023-04-07
Contact:
Zhao Haijin, Email: Supported by:
摘要:
哮喘是一种遗传和环境因素共同作用的异质性疾病,气道上皮损伤是哮喘患者常见的气道病理改变。气道上皮的物理屏障功能和免疫调节功能共同应对病毒、过敏原及大气污染物的刺激和损伤后修复,并在哮喘气道炎症、气道高反应性及气道重塑中发挥重要作用。近年来,针对气道上皮的靶向疗法已经显示出临床治疗价值,有可能成为哮喘,尤其是重度哮喘新的干预靶点。本文将重点探讨气道上皮在哮喘发病中的作用及靶向哮喘气道上皮的治疗策略。
中图分类号:
黄俊文, 陈颖, 蔡绍曦, 赵海金. 靶向哮喘气道上皮研究进展[J]. 结核与肺部疾病杂志, 2023, 4(2): 153-157. doi: 10.19983/j.issn.2096-8493.20230021
Huang Junwen, Chen Ying, Cai Shaoxi, Zhao Haijin. Research progress of targeting bronchial epithelium in asthma[J]. Journal of Tuberculosis and Lung Disease, 2023, 4(2): 153-157. doi: 10.19983/j.issn.2096-8493.20230021
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