结核与肺部疾病杂志 ›› 2023, Vol. 4 ›› Issue (5): 413-418.doi: 10.19983/j.issn.2096-8493.20230075

• 综述 • 上一篇    下一篇

胸闷变异性哮喘与典型哮喘的研究进展

郭晶1, 娄南南1, 李佳琳1, 张华1, 马香1,2,3()   

  1. 1山东大学附属儿童医院呼吸科,济南 250022
    2济南市儿童呼吸病重点实验室/济南市儿童医院,济南 250022
    3山东省儿童健康与疾病研究中心/济南市儿童医院,济南 250022
  • 收稿日期:2023-06-19 出版日期:2023-10-20 发布日期:2023-10-16
  • 通信作者: 马香,Email:maxiang0176@163.com
  • 基金资助:
    济南市临床医学科技创新计划(202134067);济南市临床医学科技创新计划(202225022);2022年济南市卫生健康委员会大数据科技计划项目(2022-BD-13);山东省儿童健康与疾病临床医学研究中心(SDPRC009);山东省自然科学基金项目(ZR2021MH147)

Research progress of chest tightness variant asthma and comparison with typical asthma

Guo Jing1, Lou Nannan1, Li Jialin1, Zhang Hua1, Ma Xiang1,2,3()   

  1. 1Department of Respiratory Disease, Children's Hospital Affiliated to Shandong University, Ji'nan 250022, China
    2Key Laboratory of Pediatric Respiratory Disease, Ji'nan Children's Hospital, Ji'nan 250022, China
    3Shandong Provincial Clinical Research Center for Children's Health and Disease, Ji'nan Children's Hospital, Ji'nan 250022, China
  • Received:2023-06-19 Online:2023-10-20 Published:2023-10-16
  • Contact: Ma Xiang,Email:maxiang0176@163.com
  • Supported by:
    Clinical Science and Technology Innovation Plan in Ji'nan(202134067);Clinical Science and Technology Innovation Plan in Ji'nan(202225022);Big Data Technology Plan Project of Ji'nan Municipal Health Commission(2022-BD-13);Shandong Provincial Clinical Research Center for Children's Health and Disease(SDPRC009);Shandong Provincial Natural Science Program(ZR2021MH147)

摘要:

哮喘作为一种慢性气道疾病,在全球引发广泛关注。胸闷变异性哮喘(chest tightness variant asthma,CTVA)是2013年提出的一类以胸闷为唯一症状的哮喘分型,由于CTVA概念的提出时间尚短,症状更不典型,使得部分医疗人员及普通人群对其认知不足,尤其对于难以描述症状的儿童患者更易造成漏诊和误诊。因此,笔者整理了近年来有关CTVA的研究,总结其临床表现、病理机制、疾病分期、诱发因素、重症发作、并发症、辅助检查、治疗方案等内容,并与典型哮喘进行比对,以提高临床医生对CTVA的认识和诊治能力。

关键词: 哮喘, 胸闷, 气道阻塞, 疾病特征, 综述文献(主题)

Abstract:

As a chronic respiratory disease, asthma is a global concern. Chest tightness variant asthma (CTVA) is a type of asthma with chest tightness as the only symptom proposed in 2013, as the concept of CTVA was proposed in a short time and the symptoms were even more atypical, some medical personnel and the general population had insufficient cognition of CTVA, and it was more likely to cause underdiagnosis and misdiagnosis for children whose symptoms were difficult to describe. In order to improve the understanding of CTVA and diagnosis and treatment ability of clinicians, this review summarized the clinical symptoms, pathological mechanism, disease stage, triggering factors, severe attack, complication, auxiliary examination and therapy of CTVA and compared it with typical asthma.

Key words: Asthma, Chest tightness, Airway obstruction, Disease attributes, Review literature as topic

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