结核病与肺部健康杂志 ›› 2019, Vol. 8 ›› Issue (3): 203-208.doi: 10.3969/j.issn.2095-3755.2019.03.011

• 论著 • 上一篇    下一篇

2015—2017年东莞市学校结核病流行病学特征分析

钟明浩(),梅月志   

  1. 523000 广东省东莞市第六人民医院防保股(钟明浩),结核病科(梅月志);
  • 收稿日期:2019-03-04 出版日期:2019-09-30 发布日期:2019-10-15
  • 通信作者: 钟明浩 E-mail:380082268@qq.com

Analysis of characteristics of tuberculosis cases in schools in Dongguan city from 2015 to 2017

ZHONG Ming-hao(),MEI Yue-zhi.   

  1. Department of Prevention and Health Care,Dongguan Sixth People’s Hospital,Guangdong Province, Dongguan 523000,China
  • Received:2019-03-04 Online:2019-09-30 Published:2019-10-15
  • Contact: Ming-hao ZHONG E-mail:380082268@qq.com

摘要:

目的 分析东莞市学校结核病流行病学特征,为完善学校结核病防治措施提供依据。 方法 从《中国疾病预防控制信息系统》子系统《传染病报告信息管理系统》和《结核病信息管理系统》中,收集2015—2017年完成抗结核药物治疗疗程的学校结核病患者总例数、发病率,以及报告患者的性别、年龄、学校分布、疾病分类、发病时间和教育阶段等资料。从东莞市统计局《2017年东莞市统计年鉴》获取2017年和之前的全人口统计资料;从东莞市教育局《东莞市2015/2016/2017/2018学年各类学校基本情况总表》获取东莞市学生和教师人口统计资料。采用SPSS 21.0软件对学校结核病报告患者数据进行人口学特征和疾病特征的统计学分析,以P<0.05为差异有统计学意义。结果 2015—2017年东莞市累计报告学校结核病患者224例,年均报告发病率为4.54/10万(224/4929416),其中学生年均发病率(3.97/10万,186/4682822)低于教师(15.41/10万,38/246594)(χ 2=67.45,P=0.000)。2015—2017年学生报告发病率[依次为2.85/10万(43/1506393)、4.38/10万(68/1554199)、4.62/10万(75/1622230)]有逐年递增趋势( χ 趋势 2 =6.05,P<0.01),而教师报告发病率[12.78/10万(10/78219)、17.21/10万(14/81343)、16.09/10万(14/87032)]无逐年递增趋势( χ 趋势 2 =0.28,P=0.600)。学生患者和教师患者男∶女分别为1.55∶1(分别为113例和73例)和0.65∶1(分别为15例和23例),差异均无统计学意义(χ 2=1.62,P=0.445;χ 2=0.63,P=0.730);15~19岁年龄组学生患者占总报告学生患者例数的67.74%(126/186);普通中学报告学生患者构成比[53.76%(100/186)]高于其他教育阶段[46.24%(86/186)](χ 2=144.78,P<0.05)。中等职业技术学校学生年报告发病率[分别为4.30/10万(3/69 734)、17.40/10万(13/74 700)、32.38/10万(26/80294)]有增长趋势( χ 趋势 2 =15.82,P<0.01)。学生结核病患者以病原学阴性为主(72.04%,134/186),且每年的4月均为发病高峰期(17.74%,33/186)。 结论 2015—2017年东莞市学生报告发病率逐年递增,男生多于女生。学校结核病控制重点在中学阶段,尤其是高中和职业技术学校。

关键词: 结核, 院校, 公共卫生, 学生, 流行病学研究特征(主题)

Abstract:

Objective To provide the basis for improving the prevention and control measures of tuberculosis in schools, epidemiological characteristics of tuberculosis in dongguan schools were analyzed.Methods The total number and incidence of TB patients in schools who completed anti-TB drug treatment courses were collected from 2015 to 2017, and reported the patient’s gender, age, school distribution, disease classification, onset and education stage from the sub-systems of “Infectious Disease Report Information Management System”and “Tuberculosis Information Management System”in the Chinese Information System for Disease Control and Prevention. The whole population statistics of 2017 and before were obtained from Dongguan statistical yearbook 2017 of Dongguan municipal bureau of statistics. The demographic data of students and teachers in Dongguan city were obtained from the general table of basic conditions of various schools in Dongguan city in the academic year 2015/2016-2017/2018 issued by Dongguan education bureau. SPSS 21.0 software was used to conduct statistical analysis of demographic characteristics and disease characteristics of the data of tuberculosis patients reported by the school. P<0.05 was considered statistically significant.Results rom 2015 to 2017, a total of 224 TB patients were reported in Dongguan, and the annual reported incidence was 4.54/100000 (224/4929416). The average annual incidence of student patients (3.97/100000, 186/4682822) was lower than that of teacher patients (15.41/100000, 38/246594) (χ 2=67.45, P=0.000). From 2015 to 2017, the student reported incidence of the disease (2.85/100000 (43/1506393), 4.38/100000 (68/1554199) and 4.62/100000 (75/1622230), respectively) had an increasing trend year by year (χ 2=6.05, P<0.01). However, the teacher reported incidence of the disease (12.78/100000 (10/78219), 17.21/100000 (14/81343), and 16.09/100000 (14/87032)) did not increase year by year (χ 2=0.28, P=0.600). The ratio of male and female were 1.55∶1 (113 cases and 73 cases, respectively) and 0.65∶1 (15 cases and 23 cases, respectively), the difference was not statistically significant (χ 2=1.62, P=0.445; χ 2=0.63, P=0.730). Students aged 15-19 years accounted for 67.74% (126/186) of the total number of reported students. The proportion of patients in general middle schools was higher than that in other education stages (53.76% (100/186) vs. 46.24% (86/186))(χ 2=144.78, P<0.05). The incidence of secondary vocational and technical school students (4.30/100000 (3/69734), 17.40/100000 (13/74700), 32.38/100000 (26/80294)) showed an increased trend (χ 2=15.82,P<0.01). The reported TB in students was mainly pathogen negative (72.04%,134/186), and the incidence peak was in April (17.74%,33/186).Conclusion From 2015 to 2017, the incidence of TB reported by students increased year by year in Dongguan city, with more males than females. School TB control is focused on the secondary level, especially in high schools and vocational and technical schools.

Key words: Tuberculosis, Schools, public health, Students, Epidemiologic study characteristics as topic