结核性气管支气管狭窄的治疗研究进展

doi:10.19983/j.issn.2096-8493.2024125

摘要/Abstract

摘要：

气管支气管结核(TBTB)引起的气管支气管狭窄越来越被临床医生所重视,严重的气道狭窄可造成患者窒息,甚至死亡,危害患者的健康和生活质量。单纯抗结核药物治疗效果不理想,作者从结核性气管支气管狭窄的最新研究进展及治疗策略进行综述,内容包括介入治疗(冷冻技术、热消融技术、球囊扩张、气道内支架置入技术、硬质支气管镜技术、支气管镜显微清创技术)、局部放射性治疗、局部药物治疗、生物制剂、基因治疗及外科治疗等。在联合抗结核药物治疗的基础上,以期找到更高效的治疗方法,为提高患者的生存质量提供参考依据。

关键词: 结核, 气管, 支气管, 气管狭窄, 物理治疗技术

Abstract:

Tracheobronchial stenosis caused by tracheobronchial tuberculosis (TBTB) has been paid more and more attention to by clinicians. It endangers the health and quality of life of patients, and can lead to respiratory failure and even death in severe cases. The effect of anti-tuberculosis drugs alone is not satisfactory. The authors review the latest research progress and treatment strategies of tuberculous tracheobronchial stenosis, including interventional therapy (cryotherapy, thermal ablation, balloon dilatation, airway stent implantation, rigid bronchoscopy, microdebrider bronchoscopy), local radiotherapy, local drug treatment, biological reagents,gene therapy and surgical treatment,based on combining with anti-tuberculosis drug treatment, in order to find more efficient treatment methods and provide reference basis for improving quality of life of patients.

Key words: Tuberculosis, Trachea, Bronchi, Tracheal stenosis, Physical therapy modalities

中图分类号:

R523

张莹, 郭春辉. 结核性气管支气管狭窄的治疗研究进展[J]. 结核与肺部疾病杂志, 2025, 6(1): 87-93. doi: 10.19983/j.issn.2096-8493.2024125

Zhang Ying, Guo Chunhui. Research progress in the treatment of tuberculous tracheobronchial stenosis[J]. Journal of Tuberculosis and Lung Disease, 2025, 6(1): 87-93. doi: 10.19983/j.issn.2096-8493.2024125

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