Abstract:

Objective: To analyze the registration and characteristics of pulmonary tuberculosis in Guangzhou City from 2016 to 2023 and evaluate the effectiveness of tuberculosis control in Guangzhou, providing scientific basis for formulating tuberculosis control strategies. Methods: Using the “China Disease Prevention and Control Information System” subsystem “Tuberculosis Information Management System”, we extracted data on all clinically and laboratory-confirmed pulmonary tuberculosis and tuberculous pleurisy patients registered by their current residence in Guangzhou from January 1, 2016, to December 31, 2023, including information such as age, gender, occupation, current residence, diagnosis results, and disease type. We analyzed the data using descriptive statistics and chi-square test. Results: A total of 66716 tuberculosis cases were registered in Guangzhou from 2016 to 2023, and the annual average registration rate decreased from 59.12/100000 (9922/16783800) in 2016 to 35.92/100000 (6763/18827000) in 2023, showing a decreasing trend ($\chi_{\text {trend }}^2$=1999.652, P=0.000). There were 44892 cases of male and 21824 cases of female patients, the ratio of male to female was 2.1∶1. They were mainly 21-30 years old (24.18%, 16130/66716); highest number of cases were registered in April (6234 cases) among all months. The average annual registration rate was highest in Yuexiu District (66.73/100000, 5477/8207400) and lowest in Panyu District (39.07/100000, 8154/20872100). The highest etiologically positive rate was in Panyu District (58.20%,4746/8154), and the lowest was in Tianhe District (49.79%, 4029/8092). For patients’ occupation, the proportion of doing housework or unemployed was the highest (43.18%,28808/66716). Conclusion: From 2016 to 2023, the tuberculosis registration rate in Guangzhou showed a downward trend, and the high incidence season was in spring and summer. Men, 21-30 years old age group, Yuexiu District residents, household and unemployed people were the key groups for tuberculosis prevention and control.

Key words: Tuberculosis,pulmonary, Epidemiologic study characteristics as topic, Small-area analysis