Abstract:

Objective: To analyze the epidemiological characteristics and changing patterns of tuberculosis notified in Nan’ao County from 2005 to 2023, and to provide reference for the formulation of tuberculosis prevention and control measures in the county. Methods: Data of tuberculosis patients registered in Nan’ao County, Guangdong Province from 2005 to 2023 were extracted from the Tuberculosis Management Information System, a subsystem of China Disease Prevention and Control Information System. Annual demographic data of Nan’ao County was derived from the Nan’ao County Statistical Yearbook. Descriptive epidemiological method was used to analyze the tuberculosis surveillance report data in Nan’ao County from 2005 to 2023, and to describe the main characteristics of TB incidence. Joinpoint regression model was used to analyze the trend of tuberculosis incidence. Results: From 2005 to 2023, a total of 1636 TB cases were reported in Nan’ao County, with an average annual incidence of 134.79/100000 (1636/1213700), among which etiologically positive tuberculosis accounted for 34.72% (568/1636). The incidence curve showed a fluctuating trend (average annual percentage change (AAPC)=-5.478%, P<0.001). No obvious seasonal peak. Among the 1636 cases reported, 1211 were male and 425 were female; There were 9 rifampicin-resistant patients, all of whom were male. The age of onset was mainly 60-69 years old (415 cases, 25.37%). The main occupation was homemaker/currently unemployed (628 cases, 38.39%). Conclusion: The incidence of tuberculosis in Nan’ao County showed a decreasing trend. Prevention and control for male, elderly people, homemaker and unemployed people should be further strengthened.

Key words: Tuberculosis, pulmonary, Incidence, Epidemiologic studies, Small-area analysis