Analysis of influencing factors of premonitory sadness in lung cancer patients complicated with pulmonary tuberculosis

doi:10.19983/j.issn.2096-8493.20220053

Abstract

Abstract:

Objective: To investigate the status of premonitory sadness in lung cancer patients complicated with pulmonary tuberculosis, and the influencing factors. Methods: A total of 88 lung cancer patients complicated with pulmonary tuberculosis admitted to Wuhan Pulmonary Hospital from June 1, 2020 to December 31, 2021 were selected as the subjects. The patients were evaluated by general condition questionnaire, the preparatory grief in advanced cancer patients (PGAC), social support rating scale (SSRS), and hospital anxiety and depression scale (HADS) and functional assessment of cancer therapy (Chinese version)(FACT-G), the relevant influencing factors were analyzed. Results: The total PGAC score was (58.27±6.45), SSRS score, HADS score and FACT-G score were (36.85±8.41), (10.22±5.78) and (50.18±4.28), respectively. Pearson correlation analysis showed that scores of social support (dimensions: 17.76±4.85, 9.12±2.34, 8.68±1.22; total score: 36.85±8.41, respectively) and quality of life (50.18±4.28) were significantly negatively correlated with total score (58.27±6.45) of PGAC dimensions (r=-0.435, P<0.001; r=-0.398, P=0.008; r=-0.520, P<0.001; r=-0.484, P<0.001; r=-0.476, P<0.001), and scores of anxiety and depression were significantly positively correlated with scores of PGAC and total scores of PGAC dimensions (r=0.590, P<0.001). Multiple linear regression analysis showed that educational level (junior college or below), social support (<36.85±8.41), anxiety and depression (>10.22±5.78), and quality of life (<50.18±4.28) were the main influencing factors of premonitory sadness (t=3.043, P=0.032; t=3.844, P=0.010; t=4.843, P=0.004; t=3.754, P=0.012). Conclusion: The premonitory sadness of lung cancer patients complicated with pulmonary tuberculosis is above medium level. Clinical nursing should provide psychological intervention to patients with low educational level and social support and heavy anxiety and depression, so as to reduce the occurrence of premonitory sadness.

Key words: Tuberculosis,pulmonary, Neoplasms, Comorbidity, Grief, Factor analysis,statistical

CLC Number:

R473.73
R521

GONG Dao-min, ZHU Ling, TIAN Tian, ZHONG Zhen. Analysis of influencing factors of premonitory sadness in lung cancer patients complicated with pulmonary tuberculosis[J]. Journal of Tuberculosis and Lung Disease , 2022, 3(3): 193-197. doi: 10.19983/j.issn.2096-8493.20220053

Figures/Tables 4

因素	例数(构成比,%)	PGAC总分( $x ¯$ ±s)	t值	P值
性别			0.165	0.871
男性	46(52.3)	57.78±7.40
女性	42(47.7)	59.01±6.34
年龄组(岁)			2.289	0.032
<60	49(55.7)	56.18±8.44
≥60	39(44.3)	60.94±5.14
婚姻状况			1.563	0.126
已婚	77(87.5)	57.02±5.78
其他^a	11(12.5)	59.47±4.96
经济状况(元/月)			0.748	0.126
<10000	38(43.2)	59.89±5.14
>10000	50(56.8)	57.60±4.64
文化水平			2.895	0.012
大专以下	52(59.1)	60.62±4.85
大专及以上	36(40.9)	55.34±5.20
工作状况			0.374	0.709
在职	59(67.0)	57.68±5.24
其他^b	29(33.0)	59.88±5.62
基础疾病			1.400	0.166
有	30(34.1)	58.76±4.23
无	58(65.9)	56.46±5.16

因素	B值	s $x ¯$ 值	β值	t值	P值
常数项	40.16	6.836	-	19.530	<0.001
年龄	4.942	2.874	0.156	2.644	0.067
文化程度	-5.532	3.456	-0.235	3.043	0.032
SSRS评分	-4.398	0.263	-0.241	3.844	0.010
HADS评分	5.506	1.453	0.128	4.843	0.004
FACT-G评分	-4.052	1.133	-0.337	3.754	0.012

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量表	维度	得分
PGAC	自我意识	26.67±3.46
	疾病调整	9.04±1.76
	悲伤	8.92±1.12
	愤怒	7.41±1.05
	宗教安慰	7.38±1.06
	总分	58.27±6.45
SSRS	主观支持	17.76±4.85
	客观支持	9.12±2.34
	支持利用	8.68±1.22
	总分	36.85±8.41
HADS	焦虑	4.52±2.08
	抑郁	5.86±2.64
	总分	10.22±5.78
FACT-G	生理状况	12.42±2.62
	社会/家庭状况	15.85±2.72
	情感状况	10.74±1.98
	功能状况	14.53±2.42
	总分	50.18±4.28

因素	自我意识		疾病调整		悲伤		愤怒		宗教安慰		总分
因素	r值	P值	r值	P值	r值	P值	r值	P值	r值	P值	r值	P值
主观支持	-0.337	0.007	-0.358	0.001	-0.291	0.019	-0.370	0.003	-0.365	0.005	-0.435	<0.001
客观支持	-0.365	0.015	-0.345	0.023	-0.388	0.020	-0.239	0.403	-0.423	0.005	-0.398	0.008
支持利用	-0.381	0.003	-0.373	0.012	-0.291	0.057	-0.409	0.002	-0.259	0.042	-0.520	<0.001
SSRS总分	-0.407	0.002	-0.364	0.005	-0.342	0.008	-0.427	<0.001	-0.395	0.003	-0.484	<0.001
HADS	0.435	0.003	0.357	0.020	0.621	<0.001	0.474	0.016	0.540	<0.001	0.590	<0.001
FACT-G	-0.264	0.034	-0.562	<0.001	-0.425	<0.001	-0.304	0.014	-0.288	0.028	-0.476	<0.001