Journal of Tuberculosis and Lung Health ›› 2020, Vol. 9 ›› Issue (1): 37-43.doi: 10.3969/j.issn.2095-3755.2020.01.009
• Original Articles • Previous Articles Next Articles
BU Jing, DU Yun(), JI Xiao-kun, WU Jia-ning
Received:
2020-01-09
Online:
2020-03-30
Published:
2020-04-17
Contact:
DU Yun
E-mail:bujing_edu@sina.com
BU Jing, DU Yun, JI Xiao-kun, WU Jia-ning. Inhibitory effect of cisplatin combined with rapamycin or 3-methyladenine in lung adenocarcinoma A549 cells[J]. Journal of Tuberculosis and Lung Health , 2020, 9(1): 37-43. doi: 10.3969/j.issn.2095-3755.2020.01.009
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URL: http://www.jtbld.cn/EN/10.3969/j.issn.2095-3755.2020.01.009
组别 | m-TOR | LC3-Ⅱ | Bax | ||||||
---|---|---|---|---|---|---|---|---|---|
24h | 48h | 72h | 24h | 48h | 72h | 24h | 48h | 72h | |
对照组 | 1.000± 0.000 | 1.000± 0.000 | 1.000± 0.000 | 1.000± 0.000 | 1.000± 0.000 | 1.000± 0.000 | 1.000± 0.000 | 1.000± 0.000 | 1.000± 0.000 |
CP | 0.667± 0.013 | 0.796± 0.003 | 0.749± 0.030 | 1.489± 0.031 | 1.325± 0.007 | 1.428± 0.080 | 1.915± 0.041 | 1.346± 0.080 | 1.462± 0.029 |
CP+RAPA | 0.418± 0.007 | 0.732± 0.007 | 0.636± 0.034 | 1.686± 0.069 | 1.803± 0.083 | 1.836± 0.056 | 1.467± 0.062 | 1.133± 0.125 | 1.117± 0.070 |
CP+3-MA | 0.684± 0.024 | 0.645± 0.008 | 0.583± 0.008 | 1.376± 0.033 | 1.253± 0.072 | 1.153± 0.011 | 1.324± 0.060 | 1.864± 0.104 | 1.935± 0.068 |
F值 | 875.508 | 2485.596 | 194.807 | 149.78 | 111.599 | 167.855 | 190.581 | 52.853 | 202.118 |
P值 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
组别 | m-TOR | LC3-Ⅱ | Bax | |||
---|---|---|---|---|---|---|
48h | 72h | 48h | 72h | 48h | 72h | |
对照组 | 1.096±0.036 | 1.132±0.007 | 0.228±0.018 | 0.239±0.008 | 0.253±0.006 | 0.248±0.006 |
CP | 0.608±0.018 | 0.573±0.025 | 0.426±0.010 | 0.492±0.009 | 0.463±0.011 | 0.581±0.007 |
CP+RAPA | 0.454±0.051 | 0.402±0.009 | 0.556±0.010 | 0.571±0.009 | 0.392±0.006 | 0.287±0.009 |
CP+3-MA | 0.447±0.011 | 0.364±0.009 | 0.355±0.009 | 0.278±0.009 | 0.897±0.022 | 0.916±0.005 |
F值 | 844.495 | 1899.708 | 372.056 | 930.500 | 1100.413 | 5715.778 |
P值 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
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