Abstract: Objective To understand tuberculosis (TB) mortality and its trends in Xinmi city after the implementation of the National TB Control Programs (NTP),by analysis of TB mortality surveillance data.Methods We monitored all residents in Xinmi city for 21 years. Death registering and reporting system was established in TB control system in Xinmi and the death reporting cards were submited from 1992. The total population in Xinmi city in the first surveillace year was 684334, and it was 873664 in the 21^th year, with an annual population of 778994.Results (1)TB mortality declined from 3.95/10⁵ (27/684344) in 1992 to 0.92/10⁵ (8/873644) in 2012, with an annual decline rate of 7.0%. (2)The rank order of causes of death for TB had declined from 13^th in 1992 to 15^th in 2012. (3)The average life expectancy of TB patients had risen from 60.0 years old in 1992 to 70.0 years old in 2012. (4) Out of all deaths, the death ratio for TB fell from 0.6% in 1992 to 0.2% in 2012, with an annual reduction rate of 5.6%. (5)Out of those dead from TB, old people more than 65 years old accounted for 52.2% (187/358). The average annual mortality rate was as following: 0.07/10⁵ for 0- years old,0.22/10⁵ for 15- years old, 1.29/10⁵ for 25- years old, 1.02/10⁵ for 35- years old, 1.95/10⁵ for 45- years old, 3.90/10⁵ for 55- years old, 14.09/10⁵ for ≥65 years old.(6)Those dead from pulmonary TB accounted for 96.1% (344/358) of all TB deaths. (7)Out of those dead from all contagious diseases, 74.1% (344/464) were from TB.Conclusion TB mortality had decreased yearly with the full implementation of NTP. But it is still the leading cause of death from infectious diseases.