Abstract: Objective To analyze the cost effectiveness of the National Tuberculosis Control Programme (NTP) in Guoyang county, and to evaluate the implementation effect of the NTP.Methods An evaluation on the basis of the standards and requirements of final-term evaluation of NTP (2002—2012) was conducted.Results From 2002 to 2012, 5.4714 million Yuan had been invested in total in the county, and 9611 active tuberculosis cases had been treated successfully. It resulted in 3258 fewer deaths, 41695 fewer infections and 4170 fewer attacks of tuberculosis. Medical cost (direct social benefit) of 4.8675 million Yuan was saved, and social economic value (indirect social benefit) of 232million Yuan was retrieved.Conclusion The implementation of the NTP in Guoyang county has achieved notable social and economic benefits,which is cost-benefit in the disease control and prevention.