肥胖相关肺部疾病的防治与诱导棕色脂肪细胞策略的潜在价值

doi:10.19983/j.issn.2096-8493.20210163

摘要/Abstract

摘要：

肥胖作为一种患病率持续上升的全球性慢性代谢性疾病,对健康有着显著的影响,会增加许多慢性疾病的发病率和病亡率,包括对哮喘、肺动脉高压等多种肺部疾病的风险。笔者通过对诱导白色脂肪组织褐变和促进棕色和米色脂肪组织功能调节机体代谢的机制进行综述,以期提供一个新的对抗肥胖及肥胖相关疾病的干预策略。

关键词: 肥胖低通气综合征, 脂肪细胞,棕色, 脂肪细胞,白色

Abstract:

As a worldwide chronic metabolic disease with increasing prevalence, obesity has a significant impact on health. It increases the morbidity and mortality of many chronic diseases, including pulmonary diseases such as asthma and pulmonary hypertension. By reviewing the mechanism of regulating metabolism via inducing the browning of white adipocytes and promoting the function of brown and beige adipocytes, the authors hope to provide a new intervention strategy against obesity and obesity-related diseases.

Key words: Obesity hypoventilation syndrome, Adipocytes,brown, Adipocytes,white

中图分类号:

R563
R589.2

华剑兰, 张静. 肥胖相关肺部疾病的防治与诱导棕色脂肪细胞策略的潜在价值[J]. 结核与肺部疾病杂志, 2022, 3(1): 55-59. doi: 10.19983/j.issn.2096-8493.20210163

HUA Jian-lan, ZHANG Jing. Prevention and treatment of obesity-related pulmonary diseases and potential value of brown adipocytes[J]. Journal of Tuberculosis and Lung Disease, 2022, 3(1): 55-59. doi: 10.19983/j.issn.2096-8493.20210163

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