肺气肿肺纤维化综合征研究进展

doi:10.19983/j.issn.2096-8493.20230090

摘要/Abstract

摘要：

肺纤维化并发肺气肿(combined pulmonary fibrosis and emphysema,CPFE)是一种未被充分认识的综合征,其特征是呼吸道症状进行性恶化,影像学上表现为上叶以肺气肿为主、下叶以纤维化为主,肺功能表现为肺容量相对保留以及气体弥散能力下降,常见的合并症是肺动脉高压和肺癌,预后不佳。进一步认识CPFE疾病对临床医生的诊治工作有一定的帮助,作者总结近年来CPFE的研究进展,包括流行病学、发病机制和危险因素、临床表现、肺功能、影像学表现、诊断、治疗、合并症及预后。

关键词: 肺疾病, 肺纤维化, 肺气肿, 综述文献(主题)

Abstract:

Combined pulmonary fibrosis and emphysema (CPFE) is an underrecognized syndrome characterized by progressive deterioration of respiratory symptoms, with imaging findings of emphysema in the upper lobe and fibrosis in the lower lobe. Lung function is characterized by relative lung volume retention and gas diffusion capacity decreased. Pulmonary hypertension and lung cancer are common comorbidities and the prognosis is poor. Further understanding of CPFE disease is helpful to clinicians in the diagnosis and treatment of CPFE. Therefore, the authors summarized the research progress of CPFE in recent years, including epidemiology, pathogenesis and risk factors, clinical manifestations, lung function, imaging findings, diagnosis, treatment, complications and prognosis.

Key words: Pulmonary disease, Pulmonary fibrosis, Pulmonary emphysema, Review literature as topic

中图分类号:

R563

冯怡, 常青, 李锋. 肺气肿肺纤维化综合征研究进展[J]. 结核与肺部疾病杂志, 2023, 4(5): 425-431. doi: 10.19983/j.issn.2096-8493.20230090

Feng Yi, Chang Qing, Li Feng. Research progress of combined pulmonary fibrosis and emphysema[J]. Journal of Tuberculosis and Lung Disease, 2023, 4(5): 425-431. doi: 10.19983/j.issn.2096-8493.20230090

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