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Journal of Tuberculosis and Lung Disease ›› 2022, Vol. 3 ›› Issue (6): 517-520.doi: 10.19983/j.issn.2096-8493.20220148

• Review Articles • Previous Articles     Next Articles

Current status and prospect of screening and treatment of latent multidrug-resistant tuberculosis infection

Chen Qiuqi1, Wu Chaoling2, Zhang Peize3, Deng Guofang3()   

  1. 1. Graduate School of Guangdong Medical University, Guangdong Province, Zhanjiang 524023, China
    2. The First Clinical Medical College of Gannan Medical University, Jiangxi Province, Ganzhou 341000, China
    3. The Second Department of Pulmonary Diseases, Shenzhen Third People’s Hospital Affiliated to Guangdong Medical University, Guangdong Province, Shenzhen 518112, China
  • Received:2022-09-14 Online:2022-12-20 Published:2022-12-15
  • Contact: Deng Guofang E-mail:jxxk1035@yeah.net
  • Supported by:
    National Natural Science Foundation of China(82070016);Dengfeng Plan of Foshan Fourth People’s Hospital Construction of High Level Hospital Open Project(FSSYKF-2020001);Application of Tuberculosis Host Reaction Detection Technology in Evaluation of Curative Effect of Pulmonary Tuberculosis(G2022005);Study on the Heterogeneity Mechanism of Mycobacterium Tuberculosis and its Effect on the Clinical Prognosis of Tuberculosis(G2021015)

Abstract:

Close contacts with multidrug-resistant tuberculosis (MDR-TB) patients have a high risk of MDR-TB infection. Some of them are prone to develop latent MDR-TB infections so that they will become a key population for tuberculosis management and control. At present, the screening and treatment of latent MDR-TB infection are challenging and still unclear. Therefore, we reviewed the epidemic and the evidence of screening, management or prevention in close contact with MDR-TB.

Key words: Tuberculosis, multidrug-resistant, Contact tracing, Diagnosis, Therapeutics

CLC Number: