An update on researches of the receptors for respiratory syncytial virus infection

doi:10.19983/j.issn.2096-8493.20220105

Abstract

Abstract:

Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections and responsible for a large proportion of mortality in children and the elderly. There are no licensed vaccines available to date. Prophylaxis and therapeutic RSV-specific antibodies are limited to populations at high risk owning to high cost and uncertain clinical value. Receptors and host factors are two determinants important for virus entry and establishment of infection in vivo. The identification and understanding of viral receptors and host factors can help us to gain insight into the pathogenesis of RSV infection. Herein, we reviewed receptors and host factors that have been reported thus far. We were characterized the functions and their roles in the life cycle of RSV, trying to provide an update on the information of RSV related receptors.

Key words: Respiratory syncytial virus infections, Receptors, cytokine, Review

CLC Number:

Feng Ziheng, Xu Lili. An update on researches of the receptors for respiratory syncytial virus infection[J]. Journal of Tuberculosis and Lung Disease , 2022, 3(5): 410-414. doi: 10.19983/j.issn.2096-8493.20220105

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