Abstract: Objective To investigate the clinical characteristics of obstructive sleep apnea hypopnea syndrome(OSAHS)of male adults in different age groups.Methods A retrospective study of 223 adult male OSAHS patients was implemented,all patients were divided into youth group(≥18 years old and <40 yearsp old,72 cases),middle-aged group(≥40 years old and<60 years old,90 cases),senile group(≥60 years old,61 cases).Polysomno-graphy(PSG)and the clinical characteristics of each group were analyzed.Results Apnea hypopnea index(AHI)of youth group(52.7±16.8 times per hour)was higher compared with middle-aged group(43.3±25.2 times per hour)and senile group(33.6±18.1 times per hour)(F=9.171,P<0.05). The oxygen saturation(SaO₂)was the lowest in the youth group(68.6±14.1)% among three groups(middle-aged group(74.2±10.3)%,senile group(78.7±12.7%)(F=14.764,P<0.05).Complication rate of middle-aged group(55.6%,50/90)and senile group(73.8%,45/61)were higher than the youth group(8.3%,6/72)(χ²=63.483,P=0.000). The differences were statistically significant.Conclusion Young patients have the most serious sleep disorder and low blood oxygen among the adult male with OSAHS. Elderly patients with OSAHS have higher incidence of complications.