Abstract:

Objective To analyze the epidemiological characteristics of pulmonary tuberculosis (PTB) in Fujian Province from 2011 to 2019, providing basis for tuberculosis prevention and control strategy. Methods The data of reported PTB cards and resident population in Fujian Province from 2011 to 2019 were collected and analyzed based on “China Disease Prevention and Control Information System”. Reported incidence was calculated, and information such as demographic characteristics and diagnostic classification of the report cards were combined to analyzed the epidemiological characteristics of PTB using the SPSS 18.0. Results A total of 172003 PTB cases were reported in Fujian Province from 2011 to 2019 with an average annual reported incidence of 50.14/10⁵ (172003/343024397), and sputum smear positive patients were 47.04% (80907/172003). The reported incidences of active PTB declined from 57.65/10⁵ (21268/36894320) in 2011 to 45.82/10⁵ (18058/39410119) in 2019, and the reported incidences of patients with positive pathogen declined from 28.49/10⁵ (10 511/36894320) to 21.92/10⁵ (8637/39410119), differences of the trend changs were both statistically significant ($X^{2}_{trend}$=765.216, 901.777; both P<0.001). From 2011 to 2019, the peak of reported cases was all in January, accounting for 9.41% (16184/172003) of all. Among the reported PTB cases, male: female≈2.77∶1 (126427∶45576). The reported incidence of male and female decreased from 82.29/10⁵ (15619/18981102) and 31.54/10⁵ (5649/17913218) in 2011 to 65.56/10⁵ (13217/20161296) and 25.15/10⁵ (4841/19248823) in 2019.Differences of the trend changes were both statistically significant ($X^{2}_{trend}$=516.143, 211.541, both P<0.001). In all reported PTB cases, 45- years old group accounted for the highest proportion (18.95% (32599/172003)), and 0- year old group was the lowest (0.43% (740/172003)) every year. The reported incidence of 0- and 75- year old groups presented the increasing trend from 2011 to 2019 (the annual increase rate was 2.92% and 0.14%), while the other age groups showed negative growth. Farmer was the occupation with the highest proportion of all patients (48.48% (83390/172003)). Conclusion The reported incidence of active PTB was decreasing from 2011 to 2019. Groups of the infant, the elder, the male, and the farmer should be paid more attention in the prevention and control of tuberculosis.

Key words: Tuberculosis,pulmonary, Incidence, Epidemiologic studies, Data interpretation,statistical, Small-area analysis