结核与肺部疾病杂志  2026, Vol. 7 Issue (5): 559-563    DOI: 10.19983/j.issn.2096-8493.20260243

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《尘肺病合并肺结核诊治中国专家共识》解读

马志明()   

  1. 广州医科大学附属市八医院呼吸与危重症医学科, 广州 510440
  • 收稿日期:2026-09-03 出版日期:2026-10-20 发布日期:2026-10-19
  • 通信作者: 马志明 E-mail:mazhm7777@163.com

Interpretation of Chinese Expert Consensus on Diagnosis and Treatment of Pneumoconiosis Complicated with Pulmonary Tuberculosis

Ma Zhiming()   

  1. Department of Respiratory and Critical Care Medicine, Guangzhou Eighth People’s Hospital Affiliated to Guangzhou Medical University, Guangzhou 510440, China
  • Received:2026-09-03 Online:2026-10-20 Published:2026-10-19
  • Contact: Ma Zhiming E-mail:mazhm7777@163.com

摘要:

中华医学会结核病学分会、中华预防医学会劳动卫生与职业病分会组织呼吸病、职业病、结核病等相关领域多学科专家共同制订《尘肺病合并肺结核诊治中国专家共识》,该共识确立了尘肺病合并肺结核的整合诊断原则,明确了病理分型、影像活动性征象判断及实验室/侵入性检查的应用规范;制订了非结核分枝杆菌肺病与肺曲霉病的分层鉴别标准;规范了抗结核治疗疗程与方案、药物相互作用管控、外科与介入治疗、康复与心理干预等临床路径;同时,明确了终末期生命支持、肺移植评估及姑息关怀的适用指征,并引入国际双向筛查联合管理的防控经验。笔者系统解读《尘肺病合并肺结核诊治中国专家共识》的核心内容与循证依据,以共识提出的12个核心临床问题及13项推荐意见为框架,结合国内外补充的流行病学、诊断技术、治疗方案及防控模式相关研究证据,整合归纳了诊断策略、鉴别诊断、治疗管理、终末期管理与防控体系五大模块的核心要点。

关键词: 尘肺, 结核, 肺, 诊断, 治疗学, 指南

Abstract:

The Chinese Society for Tuberculosis of the Chinese Medical Association and the Department of Occupational Health and Occupational Diseases of the Chinese Preventive Medicine Association organized multidisciplinary experts in respiratory diseases, occupational diseases, tuberculosis and other relevant fields to jointly formulate the Chinese Expert Consensus on Diagnosis and Treatment of Pneumoconiosis Complicated with Pulmonary Tuberculosis. The consensus establishes integrated diagnostic principles for pneumoconiosis complicated with pulmonary tuberculosis, and specifies pathological classification, judgment of active imaging-based signs, and application specifications for laboratory and invasive examinations. Stratified differential diagnostic criteria for non-tuberculous mycobacterial pulmonary disease and pulmonary aspergillosis have been formulated. Clinical pathways including anti-tuberculosis treatment regimens and duration, management of drug-drug interactions, surgical and interventional therapy, rehabilitation and psychological intervention are standardized. Meanwhile, it defines applicable indications for end-stage life support, lung transplant evaluation and palliative care, and introduces international prevention-and-control experience regarding two-way screening and joint management. Based on the 12 core clinical questions and 13 recommendations proposed in the consensus, the authors systematically interpret the core contents and evidence-based rationale of this consensus. Combined with supplementary domestic and international research evidence on epidemiology, diagnostic techniques, therapeutic regimens and prevention-control models, this paper summarizes the key points of five modules: diagnostic strategies, differential diagnosis, treatment and management, end-stage management, and prevention-control systems.

Key words: Pneumoconiosis, Tuberculosis, pulmonary, Diagnosis, Therapeutics, Guidebooks

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