结核病与肺部健康杂志 ›› 2012, Vol. 1 ›› Issue (1): 11-14.

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结核病内科治疗的现状与展望

唐神结,肖和平   

  1. 200433 同济大学附属上海市肺科医院结核病诊疗中心
  • 收稿日期:2012-06-26 出版日期:2012-07-20 发布日期:2012-07-20
  • 通信作者: 肖和平,Email:xiaoheping_sars@163.com

Current medical treatment of tuberculosis and its prospects

TANG Shen-jie, XIAO He-ping   

  1. Tuberculosis Center for Diagnosis and Treatment, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China
  • Received:2012-06-26 Online:2012-07-20 Published:2012-07-20
  • Contact: XIAO He-ping, Email:xiaoheping_sars@163.com

摘要: 结核病的内科治疗从最初的静养疗法、萎陷疗法,到1944年链霉素的问世及化学治疗时代,再到1965年利福平的问世及短程化疗时代,以及今天的化疗、免疫、介入等多种治疗并举的时代。面对日益加剧的耐药结核病的流行趋势,结核病内科治疗的未来无疑应着眼于抗结核新药的研制与开发、结核病治疗性疫苗的研究,以及纳米技术在结核病中的应用等。

Abstract: Medical treatment for tuberculosis has mutated from sanatoria treatment, artificial pneumothorax and artificial pneumoperitoneum therapy at the beginning to the emergence of streptomycin and chemotherapy, and then to the advent of rifampicin and short course chemotherapy, finally to current combined treatment, including chemotherapy, immunotherapy and intervention. Facing the trend of deteriorated drug resistance, medical treatment for tuberculosis in future will no doubt to be focusing on the research and development of new anti-TB drugs, the research of therapeutic vaccines as well as the application of nanotechnology in TB.