晚期非小细胞肺癌的内科治疗

摘要/Abstract

摘要： 晚期非小细胞肺癌5年生存率不到5%,临床多采用化疗、靶向治疗等多种方法综合治疗。近年来随着分子靶向治疗药物,如人表皮生长因子酪氨酸激酶抑制剂、新生血管抑制剂、抗肿瘤单克隆抗体及多靶点药物的出现,晚期非小细胞肺癌患者的总生存时间得到显著延长,生活质量得到明显改善。分子靶向治疗已成为最有希望且能显著改善晚期非小细胞肺癌患者预后的治疗方法。

Abstract: The 5-year survival rate of advanced non-small cell lung cancer(NSCLC), is less than 5%. Clinically chemotherapy and targeted therapy are currently used in NSCLC treatment. In recent years, with the emergence of molecular targeted therapy drugs, such as human epidermal growth factor tyrosine kinase inhibitors, angiogenesis inhibitors, the anti-tumor monoclonal antibodies and multi-target drugs, the overall survival of advanced non-small cell lung cancer had been extended significantly and the quality of patient’s life improved remarkably. Molecular targeted therapy has become the most promising treatment and can significantly improve the prognosis of advanced NSCLC.

张树才,张卉. 晚期非小细胞肺癌的内科治疗[J]. 结核病与肺部健康杂志, 2012, 1(1): 15-21.

ZHANG Shu-cai,ZHANG Hui. Medical therapy for advanced non-small-cell lung cancer[J]. Journal of Tuberculosis and Lung Health, 2012, 1(1): 15-21.

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