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Journal of Tuberculosis and Lung Disease ›› 2020, Vol. 1 ›› Issue (2): 174-178.doi: 10.3969/j.issn.2096-8493.2020.02.017

• Review Articles • Previous Articles     Next Articles

Application progress of proteome in research of the Mycobacterium tuberculosis infection

FENG Feng, TANG Feng-zhen, YAO Ming-mei, CHENG Lu, DU Li-jun()   

  1. Bacteriological Laboratory, Affiliated Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District), Southern Medical University, Guangzhou 510800, China
  • Received:2020-07-13 Online:2020-09-30 Published:2020-10-15
  • Contact: DU Li-jun E-mail:147372970@qq.com

Abstract:

China is one of the countries with high burden of tuberculosis worldwide. The drug-resistant mycobacterium tuberculosis increases the difficulties of prevention and treatment of tuberculosis. Because of the new subjects such as genomes, transcriptomics and proteomes, researches of pathogens, diagnosis, treatment and drug resistance of tuberculosis get more comprehensive and complete. Proteome is a chromatography and mass spectrometry-based Biomics technology of the separation, identify and quantify of proteins. We reviewed the progress of proteomics on pathology, diagnosis and treatment of tuberculosis, in order to provide clues and ideas for its further application in treatment and prevention of tuberculosis.

Key words: Mycobacterium tuberculosis, Proteomics, Early diagnosis, Review literature as topic