Abstract:

Objective: To analyze the epidemiological characteristics of hospitalized patients with extrapulmonary tuberculosis in Xinjiang Uygur Autonomous Region from 2018 to 2022. Methods: A retrospective study was conducted to collect the information of 4520 inpatients with extrapulmonary tuberculosis from the medical record system of the Eighth Affiliated Hospital of Xinjiang Medical University from January 1, 2018 to December 31, 2022, including gender, age, nationality, occupation, address, admission diagnosis, cumulative location of the focus, etiology examination results, clinical symptoms, discharge diagnosis, etc. Descriptive analysis was used to analyze the sociodemographic and clinical characteristics, and the risk factors for multiple types of extrapulmonary tuberculosis were analyzed using multivariate logistic regression model. Results: Among the 4520 patients with extrapulmonary tuberculosis, the most patients were admitted in the second quarter (April to June), with a total of 1327cases (29.4%); there were 2844 (62.9%) female patients and 1676 (37.1%) male patients; the number of patients aged 25-34 was the highest (n=1026, 22.7%); the most patients were cadres and staff (n=853, 18.9%); there were 2237 (49.5%) Uyghur patients; 1510 (33.4%) patients were from the southern Xinjiang and 2387 (52.8%) patients were from the northern Xinjiang. Among patients with extrapulmonary tuberculosis, lymph node tuberculosis was the most common, with a total of 1326 (29.3%) cases; 1031 patients (22.8%) had two or more types of extrapulmonary tuberculosis. Multivariate logistic regression analysis showed that, with simple extrapulmonary tuberculosis as a reference, male (OR(95%CI)=1.207 (1.046-1.393)) and fever (OR(95%CI)=1.185 (1.016-1.381)) were risk factors for the combination of multiple extrapulmonary tuberculosis. Conclusion: The proportion of lymph node tuberculosis in extrapulmonary tuberculosis in Xinjiang is the highest, and there are more female patients, more patients were young and middle-aged, and more patients were in southern Xinjiang. In clinical practice, we should focus on early screening and standardized diagnosis and treatment, and extrapulmonary tuberculosis should be included in China’s tuberculosis prevention and control planning and management as soon as possible, and then gradually form a systematic and perfect diagnosis, treatment and prevention system according to local conditions.

Key words: Extrapulmonary tuberculosis, Inpatients, Population characteristics, Disease attributes