Analysis of epidemic features of smear-positive pulmonary tuberculosis in Xinjiang Uygur Autonomous Region from 2010 to 2017

doi:10.3969/j.issn.2095-3755.2019.03.012

Abstract

Abstract:

Objective To analyze the epidemiological characteristics and spatial distribution of smear-positive tuberculosis (TB) patients registered in Xinjiang Uygur Autonomous Region (Xinjiang) from 2010 to 2017, to provide evidence for further exploring and developing TB prevention strategy in high TB burden areas.Methods Of the 71172 case reports of smear-positive pulmonary tuberculosis patients registered in 96 counties/cities/districts of Xinjiang from 2010 to 2017 were obtained from China Disease Prevention and Control Information System. Then general disease distribution features were analyzed using SPSS 22.0, while spatial clustering of smear-positive pulmonary tuberculosis were demonstrated using GIS and SaTScan 9.5.Results From 2010 to 2017, 71172 registered smear positive pulmonary tuberculosis patients were registered in Xinjiang, of which 54450 were new patients, accounting for 29.01% (71172/245339) of all patients. The average annual smear positive registration rate was 39.32/100000 (71172/181024701), showing a gradually descending trend (52.87/100000-30.69/100000). Spatial scanning analysis showed that those new smear positive patients mainly aggregated in 7 clustering areas, within which one cluster area including 29 counties/cities/districts in Kashgar, Aksu and Hotan was the largest (35.5/100000;RR=3.4, LLR=2701.28, P<0.01).Conclusion The registration rates of smear-positive pulmonary tuberculosis in Xinjiang from 2010 to 2017 were declining. New cases in Kashgar, Aksu and Hetian prefectures showed a spatial aggregation, which should be the focus area for prevention and control in the future.

Key words: Tuberculosis, pulmonary, Epidemiologic study characteristics as topic, Registries, Incidence, Space-time clustering, Data interpretation, statistical

WANG Xi-jiang,WANG Sen-lu,ZHAO Zhen,ZHANG Jing, ,TAI Xin-rong,CUI Yan.. Analysis of epidemic features of smear-positive pulmonary tuberculosis in Xinjiang Uygur Autonomous Region from 2010 to 2017[J]. Journal of Tuberculosis and Lung Health , 2019, 8(3): 209-217. doi: 10.3969/j.issn.2095-3755.2019.03.012

Figures/Tables 8

References 11

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年度	人口数 (名)	活动性肺结核		涂阳肺结核及治疗分类
年度	人口数 (名)	登记例数	登记率 (/10万)	登记例数	登记率 (/10万)	初治例数	初治登记率(/10万)	复治例数	复治登记率(/10万)
2010	21586339	25461	117.94	11412	52.87	9013	41.75	2399	11.11
2011	21815819	23101	105.89	9392	43.05	7285	33.39	2107	9.66
2012	22087038	28514	129.10	11150	50.48	8673	39.27	2477	11.21
2013	22327803	30435	136.31	8456	37.87	6424	28.77	2032	9.10
2014	22643000	31049	137.12	7942	35.07	5903	26.07	2039	9.00
2015	22984695	32898	143.13	7658	33.32	5718	24.88	1940	8.44
2016	23600000	34395	145.74	7243	30.69	5486	23.25	1757	7.44
2017	23980007	39486	164.66	7919	33.02	5948	24.80	1971	8.22
合计	181024701	245339	135.53	71172	39.31	54450	30.08	16722	9.24

聚集区	实际患者例数	期望患者例数	预测初治涂阳登记率(/10万)	RR值	LLR值	P值	聚集性县(区、市)
第一区	27872	19466	35.5	1.88	2701.28	<0.001	库车县、沙雅县、拜城县、乌什县、新和县、阿瓦提县、柯坪县、阿克陶县、英吉沙、泽普县、莎车县、叶城县、麦盖提县、岳普湖县、伽师县、疏勒县、皮山县、墨玉县、和田县、和田市、且未县、民丰县、于田县、洛浦县、阿合奇、阿克苏市、温宿县、策勒县、巴楚县
第二区	7564	5335	35.2	1.49	463.19	<0.001	巩留县、昭苏县、新源县、尼勒克县、塔城市、额敏县、托里县、和布赛尔县、阿勒泰市、富蕴县、哈巴河县、吉木乃县、特克斯县、精河县、博乐县
第三区	1528	1083	35.0	1.42	82.71	<0.001	霍城县、察县
第四区	735	454	40.1	1.63	73.61	<0.001	尉梨县、若羌县
第五区	929	659	35.0	1.42	49.81	<0.001	焉煮县、博湖县、和静县
第六区	465	306	37.6	1.52	35.58	<0.001	青河县、福海县
第七区	1099	923	29.5	1.19	16.12	<0.001	乌恰县、疏附县

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