结核病与肺部健康杂志 ›› 2017, Vol. 6 ›› Issue (3): 275-278.doi: 10.3969/j.issn.2095-3755.2017.03.000

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氟喹诺酮类药物在结核病治疗中的研究进展

程燕芝,刘群群,苗艳芳,唐神结   

  1. 030053 太原市第四人民医院耐药结核二科(程燕芝、刘群群、苗艳芳);首都医科大学附属北京胸科医院 北京市结核病胸部肿瘤研究所(唐神结)
  • 收稿日期:2017-07-15 出版日期:2017-09-30 发布日期:2017-09-30
  • 作者简介:唐神结

Advances in the study of fluoroquinolones in the treatment of tuberculosis

CHENG Yan-zhi ,LIU Qun-qun, MIAO Yan-fang, TANG Shen-jie   

  1. Second cases of drug-resistant tuberculosiss, the Fourth People,s Hospital of Taiyuan.Taiyuan 030053,China
  • Received:2017-07-15 Online:2017-09-30 Published:2017-09-30

摘要: 近年来,关于氟喹诺酮类药物在结核病治疗中的研究越来越多。氟喹诺酮类药物对结核分枝杆菌具有很强的杀菌与灭菌作用,在临床治疗结核病中起到了重要作用,但在临床应用中也存在着很多不合理的现象。笔者综述了氟喹诺酮类药物在初治、复治、耐药结核病治疗中的研究进展,以便为临床上更好地选择氟喹诺酮类药物治疗结核病提供参考。

Abstract: In recent years, more and more studies have been focused on the treatment of tuberculosis by fluoroquinolones. Fluoroquinolones have strong bactericidal effects on Mycobacterium tuberculosis. At present, it plays an important role in the clinical treatment of tuberculosis. However, there are many unreasonable phenomena in its application. In this review, we reviewed the progress of fluoroquinolones application in the treatment of newly diagnosed, recurrent, and drug-resistant tuberculosis, in order to provide a basis for better selection of fluoroquinolones in the treatment of tuberculosis.