结核病与肺部健康杂志 ›› 2014, Vol. 3 ›› Issue (1): 64-67.doi: 10.3969/j.issn.2095-3755.2014.01.014

• 综述 • 上一篇    下一篇

细胞因子与糖尿病并发结核病关系的研究进展

李雨泽,李楠,李晓南,姜岩,李殿忠   

  1. 150500 哈尔滨,黑龙江省传染病防治院内四科
  • 收稿日期:2013-06-24 出版日期:2014-03-30 发布日期:2014-03-30
  • 通信作者: 李殿忠,Email:lidianzhong2010@163.com
  • 基金资助:
    黑龙江省卫生厅科研课题(2012-431)

Research progress of the association between cytokine and diabetes mellitus complicated with tuberculosis

LI Yu-ze, LI Nan, LI Xiao-nan, JIANG Yan, LI Dian-zhong   

  1. The Fourth Medical Department of Heilongjiang Provincial Tuberculosis Control Center, Harbin 150500, China
  • Received:2013-06-24 Online:2014-03-30 Published:2014-03-30
  • Contact: LI Dian-zhong,Email:lidianzhong2010@163.com

摘要: 全球有1/3的人口曾受到结核分枝杆菌的感染。结核病与糖尿病关系密切,糖尿病患者被认为是结核病易感人群之一,具有感染率高、肺结核患病率高、死亡率高的特点。笔者针对某些细胞因子的改变对糖尿病并发结核病患病率及临床治愈率的影响进行综述,并介绍了近年来国内外研究现状。笔者还从细胞因子免疫方面对糖尿病并发结核的高患病率现象进行了解释,对糖尿病并发结核的发病机制及临床早预防、早发现及早治疗给予了介绍。

Abstract: One third of the world’s population has been infected with mycobacterium tuberculosis. Tuberculosis (TB) is closely associated with diabetes mellitus (DM), and DM patient is regarded as one of the TB susceptible population, with high infection rate, high TB prevalence and high mortality rate as characteristics. Through reviewing relevant literatures in recent years, this paper introduces the domestic and overseas research status of effect of some cytokine changes on the prevalence and clinical cure rate of DM complicated with TB. The high prevalence of DM complicated with TB is also explained from the aspects of cytokine immune. The basic information of the pathogenesis, early detection and treatment of DM complicated with TB are introduced as well.