耐药结核病辅助治疗的进展

doi:10.3969/j.issn.2095-3755.2013.04.002

结核病与肺部健康杂志 ›› 2013, Vol. 2 ›› Issue (4): 222-227.doi: 10.3969/j.issn.2095-3755.2013.04.002

耐药结核病辅助治疗的进展

曾熙玲,初乃惠,刘志敏

101149 首都医科大学附属北京胸科医院结核一科(曾熙玲、初乃惠);山东省胸科医院(刘志敏)

收稿日期:2013-11-13 出版日期:2013-11-30 发布日期:2013-11-30
通信作者: 初乃惠,Email:dongchu1994@sina.com
基金资助:
“十二五”国家科技重大专项(2012ZX09303002)

Progress on adjuvant treatment of drug-resistant tuberculosis

ZENG Xi-ling^*, CHU Nai-hui, LIU Zhi-min

^*The First Department of Tuberculosis, Beijing Chest Hospital Affiliated to Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China

Received:2013-11-13 Online:2013-11-30 Published:2013-11-30
Contact: CHU Nai-hui,Email:dongchu1994@sina.com

摘要/Abstract

摘要： 耐药结核病是国内外结核病控制的重点和难点。近年来,不少学者应用免疫制剂辅助治疗耐药结核病取得了一定的疗效。目前研究较多的有细胞因子制剂和分枝杆菌疫苗等,但这些免疫制剂在耐药结核病的治疗中疗效不同,部分研究取得了较好的结果,但部分研究疗效不明显。笔者对国内外细胞因子制剂和其他免疫制剂辅助治疗耐多药结核病(multidrug-resistant tuberculosis, MDR-TB)的现状进行了回顾与复习,期望为免疫制剂辅助治疗耐药结核病的应用提供参考。

Abstract: Drug-resistant tuberculosis (TB) is the keystone and difficulty in TB control at home and abroad. In recent years, many scholars have applied immune agents in the adjuvant treatment of drug-resistant TB and obtained positive efficacy. Currently the most active research of immune agents are cytokines and mycobacterial vaccine formulations. However, the effects of these immune agents in the treatment of drug resistant TB are different, some have achieved good results, but others have no obvious effect. The paper reviews the leukemia cytokine and other immune agents that play an immunotherapy role in the adjuvant treatment of drug resistant TB, and it is anticipated to provide reference for the application of immune agents in the adjuvant treatment of drug resistant TB.

曾熙玲,初乃惠,刘志敏. 耐药结核病辅助治疗的进展[J]. 结核病与肺部健康杂志, 2013, 2(4): 222-227. doi: 10.3969/j.issn.2095-3755.2013.04.002

ZENG Xi-ling, CHU Nai-hui, LIU Zhi-min. Progress on adjuvant treatment of drug-resistant tuberculosis[J]. Journal of Tuberculosis and Lung Health, 2013, 2(4): 222-227. doi: 10.3969/j.issn.2095-3755.2013.04.002

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耐药结核病辅助治疗的进展

Progress on adjuvant treatment of drug-resistant tuberculosis

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