Analysis of specimens examination results of patients with tuberculosis after surgery by using two laboratory techniques

doi:10.3969/j.issn.2095-3755.2020.01.017

Abstract

Abstract:

A total of 60 patients, who had been suspected diagnosed as tuberculosis (TB) and received surgery at department of thoracic surgery of Anhui Provincial Hospital from June 2017 to January 2019, were enrolled in this study. The lung tissue specimens were obtained from those enrolled patients. GeneXpert MTB/RIF and acid-fast staining tests were performed on all patients’ pathological specimens to evaluate the value of GeneXpert MTB/RIF and acid-fast staining on detection of pulmonary TB with their surgical tissue specimens. In 60 patients, the positive rate of GeneXpert MTB/RIF and acid-fast staining was 46.7% (28/60) and 48.3% (29/60) respectively. Five specimens with acid-fast staining positive but GeneXpert MTB/RIF negative were confirmed to be Mycobacterium tuberculosis (MTB) by mycobacteria identification. The positive rate of both GeneXpert MTB/RIF and acid-fast staining was 55.0% (33/60), which met the target of 50% pathogenic detection rate at least required in the 13th Five-year National TB Control Program. In conclusion, the TB detection rate is high by jointly using GeneXpert MTB/RIF and acid-fast staining and it’s valuable in clinical diagnosis of TB.

Key words: Tuberculosis, pulmonary, Pathology, Nucleic acid amplification techniques, Diagnostic techniques and procedures

GONG Ya-ya, LU Huai-wei, WANG Qi, CAO Le-jie. Analysis of specimens examination results of patients with tuberculosis after surgery by using two laboratory techniques[J]. Journal of Tuberculosis and Lung Health , 2020, 9(1): 79-81. doi: 10.3969/j.issn.2095-3755.2020.01.017

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