Abstract: Tuberculosis (TB) is a chronic infectious disease. It is still a significant public health concern as the prevalence of TB infection and prevalence remains high in China. However, TB infection control work is gene-rally inadequate and is considered to be the weak link in TB control worldwide. Very few studies on TB infection control have been performed in China. Previous research findings indicated that health care workers (HCWs) are at higher risk of TB infection and disease in comparison with the general population. Currently, the implementation of regular screening of TB infection and disease, protective measures and powerful TB infection control policy are not systematically performed in China. Therefore, strengthening TB infection control in HCWs has become an urgent public health priority. In order to protect the HCWs and reduce their risk of TB infection and disease, TB infection control program should be integrated with the general infection control program and bring it into the National Tuberculosis Control Program.