Abstract:

Objective To study the correlation between nutritional risk status and clinical characteristics of pulmonary tuberculosis patients. Methods To collected the nutritional risk profile and clinical features of information (including sex, age, time, type, extrapulmonary tuberculosis, complications, patients with respiratory tract specimens, respiratory specimens of acid-fast stain BACTEC MGIT 960 liquid culture) of 313 cases tuberculosis patients admitted to TB Division of Chengdu Public Health Clinical Center from Jan to May, 2019. Nutritional risk was assessed by Nutritional Risk Screening 2002, including nutritional status score, disease severity score and age score, the total score is 0-7. Single linear regression analysis was carried out for each clinical feature, and the correlation between nutritional risk and clinical characteristics of pulmonary tuberculosis patients was analyzed by multiple linear regression. Results The nutritional risk assessment score of 313 patients based on Nutritional Risk Screening 2002 was 0-7, with an average score of 4.06±1.27; 279 patients with scores ≥3 points, accounting for 89.1%, 34 patients with scores <3 points, accounting for 10.9%. Among them, the average score of nutritional status was 2.49±1.03, the average score of disease severity was 1.02±0.07, and the average score of age was 0.07±0.01. Single linear regression analysis showed that age 60 years or more (t=7.653, P=0.002), disease onset period (t=10.558, P=0.001), the types of patients (t=2.305, P=0.002), concurrent extrapulmonary tuberculosis (t=4.755, P=0.016), complications (t=45.343, P=0.017) had a statistically significant difference in nutritional risk score. The results of multiple linear regression analysis showed that age elder than 60 years old (t=1.345, P=0.016), time of onset (t=3.986, P=0.001) and complications (t=8.569, P<0.001) were the factors that affected the nutritional risk. Conclusion Elderly pulmonary tuberculosis patients, time of onset and complications are the risk factors affecting the nutritional risk status of pulmonary tuberculosis patients.

Key words: Tuberculosis, pulmonary, Disease attributes, Nutrition assessment, Regression analysis