Abstract: Objective To evaluate the implementation effect of Zhangdian tuberculosis control and prevention programme in Zibo city of Shandong province from 2001 to 2012,and to provide scientific evidence for sustainable development of TB control. Methods The referral and tracing situation of 1929 TB suspects from 2005 to 2010, of which data were from the annual report of the TB management information system of Zhangdian were collected and analyzed, as well as the detection, treatment and management situation of 2395 TB patients registered from 2001 to 2012. Results (1)A total of 2395 active pulmonary tuberculosis cases were detected from 2001 to 2012,among which 1297 were smear positive cases and 1160 were new smear positive cases.The registration rate of active pulmonary tuberculosis was 32.56/100 000 (2395/7 355 400), and that of new smear positive cases was 15.77/100 000 (1160/7 355 400).(2)The referral rate of TB suspects was 96.58% (1863/1929), the tracing arrival rate was 85.87% (808/941), and the overall arrival rate of TB suspects was 81.49% (1572/1929) during 2005—2012. (3)The treatment success rate of active pulmonary tuberculosis was 95.16% (2279/2395), the cure rate of smear positive cases was 92.91% (1205/1297), and that of new smear positive cases was 94.05% (1091/1160) from 2001 to 2012. Conclusion Zhangdian has made substantial progress on TB control, while there are still some new challenges and difficulties to be addressed during the implementation of the twelfth five-year plan.