Abstract:

Chronic obstructive pulmonary disease (COPD) is a common chronic airway inflammatory disease with complex pathogenesis, and cellular or molecular mechanisms remain unknown. Airway inflammation is one of the treatable features, however, current diagnostic methods can not reflect the heterogeneity of airway inflammation in such patients, and the treatment limitations are obvious. In recent years, in large number of clinical trials, it has been a shown that the level of blood eosinophils is closely related to COPD response, deterioration risk, mortality and length of stay in the hospital of COPD, but the mechanism is not very clear. Therefore, the author reviewed the formation process, diagnosis, traditional glucocorticoids and new target therapy of eosinophilic COPD, to provide reference for eosinophils as a new potential biomarker and treatable feature of COPD.

Key words: Oxyphil cells, Pulmonary disease,chronic obstructive, Individualized medicine