Abstract:

Objective To investigate whether incidence of nutritional risk is associated with the clinical characteristics of patients with intestinal tuberculosis and to provide the guideline with the patients for the needs of the reasonable nutrition treatment. Methods Two hundred and three patients admitted to the Chest Hospital of Xinjiang Uyghur Autonomous Region identified as having laboratory- and clinical-confirmed intestinal tuberculosis. Data were collected from January 2016 to January 2019. Of the 203 patients studied and by age, 97 patients admitted to the youth group (group A1, less than 44 years), 64 patients to the middle age group (group A2, 45 to 60 years) and 42 patients to the old age group (group A3, more than 60 years). Or by lesion site, 38 patients admitted to the simple ileum terminal group (group L1), 23 patients to the colonic group (group L2), 68 patients to the ileum and colon group (group L3), and 20 patients to the upper gastrointestinal tract group (group L4), 54 patients to the upper digestive tract and ileum terminal or colon or ileocolon group (group L4+L1/L2/L3). Or by the pathological classification, 95 patients admitted to ulcer type (type B1), 47 patients to proliferative type (type B2) and 61 patients to mixed type (type B3). Or by the disease activity stage, 159 patients admitted to active stage and 44 patients to stable period. The nutritional risk score and clinical data, collected using the European nutritional risk screening tool (NRS 2002) and standardized case reported form. Results All studied cases were evaluated by NRS 2002. The incidence of nutritional risk in patients at onset of intestinal tuberculosis was 81.28% (165/203), of which was occupied by 80.61% (79/98) in men and by 81.90% (86/105) in women (χ²=0.056,P>0.05). Also, in different age groups we observed that the incidence of nutritional risk was 74.23% (72/97) in group A1, 84.38% (54/64) in group A2 and 92.86% (39/42) in group A3, respectively (χ²=7.274,P=0.026). Additionally, in different lesion site group the incidence of nutritional risk was evaluated as the follows: 81.58% (31/38) in group L1, 56.52% (13/23) in group L2, 79.41% (54/68) in group L3, 90.00% (18/20) in group L4, and 90.74% (49/54) in group L4+L1/L2/L3, respectively (χ²=12.066,P=0.014). Moreover, in different pathological types the incidence of nutritional risk was involved in type B1, B2 and B3 with 89.47% (85/95), 72.34% (34/47) and 75.41% (46/61), respectively (χ²=8.042,P=0.018). Interestingly, in the active or stable period the incidence of nutritional risk was 89.31% (142/159) and 52.27% (23/44), respectively (χ²=31.068,P<0.001). Conclusion The occurrence of incidence of nutritional risk of hospitalized patients with intestinal tuberculosis was quite frequent, and routine nutritional risk screen was strongly recommended. Here, we also implicated that the nutritional risk screen in elderly patients, active patients, patients with upper digestive involvement, and patients with ulcerative and mixed intestinal tuberculosis should be tightly conducted.

Key words: Tuberculosis, Gastrointestinal, Nutrition assessment, Nutrition surveys, Comparative study, Factor analysis, statistical