Abstract:

Objective To analysis the current states and influencing factors of tuberculosis infection of drug addicts before compulsory isolation and rehabilitation. Methods Tuberculin skin test (TST) was used to screen the tuberculin infection of the newly admitted detoxists from April 2017 to June 2019. According to the WS 288-2017 tuberculosis diagnosis. Logistic regression was used to analyze the possible influencing factors of tuberculosis infection, with age, education level, marital status, body mass index (BMI) value, BCG scar, suspicious symptoms of tuberculosis, underlying disease, years of drug abuse, times of drug withdrawal and other factors as independent variables and infection as dependent variables. Results A total of 754 drug addicts were screened, 429 (56.9%) were positive for TST and 148 (19.6%) were strongly positive. There were 428 cases (56.8%) have a BCG scar. According to the standard, there were 379 people infected with tuberculosis, and the tuberculosis infection rate of drug addicts was 50.3%. Multivariate logistic regression analysis showed that, age (OR=1.04,P=0.001) and BMI (OR=1.08,P=0.003) were influencing factors of tuberculosis infection. Conclusion Drug addicts have a relatively high level of tuberculosis infection before compulsory isolation for drug rehab.In order to avoid the outbreak of tuberculosis epidemic, the drug treatment centers should strengthen the prevention and control of tuberculosis for drug addicts, especially those who are older and higher BMI.

Key words: Drug users, Substance abuse treatment centers, Tuberculosis, Mycobacterium infections, Multiphasic screening, Factor analysis, statistical