Virus genome, the direct way to know the SARS-CoV-2 virus

doi:10.3969/j.issn.2095-3755.2020.01.005

Abstract

Abstract:

WHO announced the COVID-19 epidemic as a global pandemic on 11 March 2020. Understanding the genome of the pathogen SARS-CoV-2 virus, and unravelling the science behind the virus will pave the way for controlling the disease. This manuscript summarized the aspects that virus genome could contribute to, including virus identification, essential gene analysis, virus origination, transmission dynamics, and epidemic prediction. Meanwhile, key directions of SARS-CoV-2 virus genomics in the current stage, and the importance of communication and collaboration are stated.

Key words: Coronavirus Infections, Genes, High-Throughput Nucleotide Sequencing

LIU Di. Virus genome, the direct way to know the SARS-CoV-2 virus[J]. Journal of Tuberculosis and Lung Health , 2020, 9(1): 16-18. doi: 10.3969/j.issn.2095-3755.2020.01.005

References 8

[1]	肖和平, 刘一典 . 新型冠状病毒疫情防控机制对结核病防治的启示. 中国防痨杂志, 2020,42(4):312-316.
[2]	Lu R, Zhao X, Li J , et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet, 2020,395(10224):565-574.
[3]	Xu X, Chen P, Wang J , et al. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. Sci China Life Sci, 2020,63(3):457-460.
[4]	Wrapp D, Wang N, Corbett KS , et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science, 2020,367(6483):1260-1263.
[5]	Zhou P, Yang XL, Wang XG , et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 2020,579(7798):270-273.
[6]	Dudas G, Carvalho LM, Bedford T , et al. Virus genomes reveal factors that spread and sustained the Ebola epidemic. Nature, 2017,544(7650):309-315.
[7]	Ni M, Chen C, Qian J , et al. Intra-host dynamics of Ebola virus during 2014. Nat Microbiol, 2016,1(11):16151
[8]	Guan Y, Zheng BJ, He YQ , et al. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science, 2003,302(5643):276-278.

[1]	Su XingYue, Wang Beilei, Ma Xiang. Single nucleotide polymorphisms and related genes in Chinese children with type 2 inflammatory asthma [J]. Journal of Tuberculosis and Lung Disease, 2024, 5(4): 370-375.
[2]	He Fanyi, Lu Nihong, Du Yingrong. Research progress on the interaction between tuberculosis and COVID-19 [J]. Journal of Tuberculosis and Lung Disease, 2024, 5(4): 345-351.
[3]	Xu Siyun, Lu Nihong. Research progress of respiratory system injury caused by novel coronavirus [J]. Journal of Tuberculosis and Lung Disease, 2024, 5(3): 267-272.
[4]	Lin Rongmei, Lu Nihong. Current status of myocardial injury associated with the coronavirus disease 2019 [J]. Journal of Tuberculosis and Lung Disease, 2023, 4(6): 493-498.
[5]	Gong Yabo, Liu Liqin, Xu Zuhui, Yang Yuan. Study on impact of COVID-19 on medical services of tuberculosis designated hospitals in Hunan Province [J]. Journal of Tuberculosis and Lung Disease, 2023, 4(4): 277-282.
[6]	Zhou Yongfang, Fu Jiangquan, Dong Wentao, Fang Donghai, Hu Xiaochun. Meta-analysis of efficacy and safety of inhaled nitric oxide in the treatment of severe and critical novel coronavirus pneumonia [J]. Journal of Tuberculosis and Lung Disease, 2023, 4(1): 33-40.
[7]	WU Di, LIN Fen, CHEN Xiao-hong, LIN You-fei, HUANG Ming-xiang, CHEN Li-zhou. Convalescent plasma therapy for two cases of rapid progressing severe COVID-19 and literature review [J]. Journal of Tuberculosis and Lung Disease, 2022, 3(1): 33-43.
[8]	WU Di, FAN Xin-xin, SHEN Jian-shan, LIN You-fei, CHEN Xiao-hong, HUANG Ming-xiang, CHEN Li-zhou. Diagnostic value of combined detection of coagulation screening indicators and D-dimer in clinical classification of COVID-19 [J]. Journal of Tuberculosis and Lung Disease, 2021, 2(4): 355-360.
[9]	LIU Xin-yu, ZHANG Qian, SUN Qian. Analysis of drug resistance of multidrug-resistant Mycobacterium tuberculosis to multiple drugs in Changping District of Beijing [J]. Journal of Tuberculosis and Lung Disease, 2021, 2(2): 169-173.
[10]	YANG Yang, LU Shui-hua. Adult-onset mendelian susceptibility to mycobacterial disease: a case report and literature review [J]. Journal of Tuberculosis and Lung Disease, 2020, 1(3): 226-232.
[11]	REN Zhen-juan, ZHANG Hai-jie, SU Yun-kai, MA Yan, LIU Yao. Correlation between amikacin resistance and rrs gene mutation in multidrug-resistant Mycobacterium tuberculosis [J]. Journal of Tuberculosis and Lung Disease, 2020, 1(2): 117-120.
[12]	TANG Zai-qing, TANG Ming-hao, ZHU Xiao-lin, LIU Yu-qin. Application value of gene chip technology in the rapid diagnosis of tuberculosis and the identification of mycobacterium [J]. Journal of Tuberculosis and Lung Health, 2020, 9(1): 55-57.
[13]	CHANG Li,LIN Hong,SUN Su-qin,PANG You-quan,BIAN Nan-nan,ZHEN Chun-ying,GUAN Xue-qing,YANG Hao,LIU Xue-mei. Effect of different expressions of ERCC1 and LRP performed on the effectiveness of cisplatin in the treatment of malignant pleural effusion [J]. Journal of Tuberculosis and Lung Health, 2019, 8(3): 178-182.
[14]	CHEN Zi-fang,WANG Feng-qing,WANG Jian,LAO Hai-li,SUN Ben-hai,CHEN Qi. The analysis of Multidrug-resistant tuberculosis and Mycobacterium strain distribution in Bin Zhou region of Shandong [J]. Journal of Tuberculosis and Lung Health, 2015, 4(4): 250-253.