Abstract: Objective To explore the effect of the self-care management model in the treatment of patients with tuberculosis among floating population.Methods We use the self-care capacity measurement scale (ESCA) to measure the self-care ability of 53 patients before and after the intervention, t test is used for statistical analysis and P<0.05 is considered statistically significant.Results After the intervention, in terms of the self-care ability,the concept of self-care, the self-care motivation, the self-care knowledge, and whether response is passive, the ave-rage scores of the 53 patients increased from 116.82±19.23 ,44.40±8.09,37.81±9.64,18.69±3.90,16.71±4.66 to 138.25±15.48 ,51.46±6.72,45.85±6.09,22.81±2.53,19.92±3.17. The differences are all statistically significant(t=27.11、6.85、5.30、10.05、7.51,P<0.05).Conclusion The self-care management model can effectively improve treatment compliance and self-care capacities for TB patients among floating population.