Study of invasive adenocarcinoma as pulmonary pure ground glass nodules with CT value less than -560HU using thin-slice CT

doi:10.3969/j.issn.2095-3755.2018.04.003

Abstract

Abstract:

Objective To explore imaging characteristics of invasive adenocarcinoma (IA) as pulmonary pure ground glass nodule (pGGN) with CT value less than -560HU using thin-slice CT.Methods One hundred and forty-four patients with pGGN of CT value less than -560HU confirmed by surgical pathology in the First Affiliated Hospital of Dalian Medical University were enrolled in this study. They were divided into two groups: 8 patients in IA and 136 in non-IA (including atypical adenomatous hyperplasia, adenocarcinoma in situ, microinvasive adenocarcinoma). All patients performed thin-slice CT scan. We measured the maximum diameters of pGGN.Results The maximum diameter of pGGN with CT value less than -560HU in IA group (2.00±0.71cm) was significantly larger than non-IA group (0.92±0.43cm)(t=-4.495,P=0.003),AUC=0.94, best cut-off value was 1.10cm, sensitivity was 100.00%.Conclusion The maximum diameter of pGGN with CT value less than -560HU is an optimum parameter to predict IA when cut-off value of maximum diameter is set up 1.10cm.

Key words: Adenocarcinoma, bronchiolo-alveolar, Solitary pulmonary nodule, Tomography, X-ray computed, Neoplasm staging, Forecasting

Shuai HU,Meng-ying LI,Si-yu CHE,Guang-qing HAN,Xin-yan LIU,Ai-lian LIU,Zhi-yong LI. Study of invasive adenocarcinoma as pulmonary pure ground glass nodules with CT value less than -560HU using thin-slice CT[J]. Journal of Tuberculosis and Lung Health , 2018, 7(4): 236-240. doi: 10.3969/j.issn.2095-3755.2018.04.003

Figures/Tables 10

临床资料	非IA组(136例)	IA组(8例)	统计学检验值	P值
年龄(岁, $x ˉ$ ±s)	56.80±10.40	62.40±7.80	-1.465^a	0.145
吸烟史[例(构成比,%)]			0.000^b	1.000
是	10(7.35)	1(12.50)
否	126(92.65)	7(87.50)
病灶CT表现
病灶最长径(cm, $x ˉ$ ±s)	0.92±0.43	2.00±0.71	-4.495^a	0.003
CT值(HU, $x ˉ$ ±s)	-648.82±54.11	-621.50±33.01	-1.387^a	0.168
胸膜牵拉征[例(发生率,%)]	2(1.47)	1(12.50)	0.986^b	0.403
空泡征[例(发现率,%)]	23(16.91)	2(25.00)	0.013^b	0.924

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