Considerations for the application of laboratory diagnostics in detecting drug-resistant tuberculosis

doi:10.3969/j.issn.2096-8493.2021.01.004

Abstract

Abstract:

Drug-resistant tuberculosis remains an important challenge for TB control. The recent development of molecular biology diagnostics overcomes the shortcomings of traditional drug-resistance diagnosis methods, which has increased its value in clinical applications, but how to make better use of molecular biological diagnostic methods for clinical service is worth to be considered. In this paper, the authors systematically analyze the current diagnostics for drug-resistant tuberculosis, and summarize the dilemmas in the clinical use of molecular diagnostics for detection of drug resistance tuberculosis, aiming to provide important clinical experience for the diagnosis and treatment of drug-resistant tuberculosis.

Key words: Drug resistance, bacterial, Mycobacterium tuberculosis, Microbial sensitivity tests, Molecular diagnostic techniques

ZHANG Zhi-guo, GUO Hai-ping, PANG Yu. Considerations for the application of laboratory diagnostics in detecting drug-resistant tuberculosis[J]. Journal of Tuberculosis and Lung Disease , 2021, 2(1): 13-17. doi: 10.3969/j.issn.2096-8493.2021.01.004

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