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Journal of Tuberculosis and Lung Disease ›› 2024, Vol. 5 ›› Issue (3): 197-206.doi: 10.19983/j.issn.2096-8493.2024048

• Original Articles • Previous Articles     Next Articles

Correlation analysis of physical activity levels and symptom clusters in lung cancer chemotherapy patients during hospitalization

Chen Xinxin1, Liu Guofeng2, Yang Yingzi3, Hu Yachen2, Jin Ying1, Li Yumei1()   

  1. 1Department of Nursing, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China
    2Department of Nursing, Tongji University School of Medicine, Shanghai 200092, China
    3Department of Health Nursing, Huadong Sanatorium, Wuxi 214100, China
  • Received:2024-03-16 Online:2024-06-20 Published:2024-06-12
  • Contact: Li Yumei,Email:13917922290@163.com
  • Supported by:
    Shanghai Pulmonary Hospital Nursing Department’s Research Project(HL202403);Teaching Reform and Construction Project of Tongji University(JS20221212)

Abstract:

Objective: Investigate the patients’ willingness to engage in exercise and level of physical activity with patients with lung cancer undergoing chemotherapy, and analyze the correlation between their physical activity level and symptom clusters. Methods: A cross-sectional survey was conducted from June to August 2022 among 232 lung cancer chemotherapy patients hospitalized at the Department of Respiratory Medicine, Shanghai Pulmonary Hospital, using a general questionnaire, the International Physical Activity Questionnaire (IPAQ), the revised version of the lung cancer module of the M.D. Anderson Symptom Inventory (MDASI-LC). A total of 229 valid questionnaires were collected, with an effective recovery rate of 98.71%. Exploratory factor analysis was employed to identify the categories of symptom clusters, and Spearman’s rank correlation analysis was used to examine the correlation between their physical activity level and symptom clusters. Results: Six symptom clusters were identified in patients with lung cancer undergoing chemotherapy: respiratory symptom cluster, sleep-related symptom cluster, psychological symptom cluster, gastrointestinal symptom cluster, lung cancer-specific symptom cluster and cachexia symptom cluster. Moderate-intensity physical activity was negatively associated with psychological and cachexia symptoms (r=-0.153, -0.159; both P<0.05), while walking activity was negatively correlated with respiratory, sleep-related, psychological, and lung cancer-specific symptom clusters (r=-0.257, -0.222, -0.284, -0.181; all P<0.05). Total physical activity level was also negatively correlated with the respiratory, sleep-related, psychological, and cachexia symptom clusters (r=-0.252, -0.218, -0.304, -0.132; all P<0.05). Conclusion: The level of physical activity in lung cancer chemotherapy patients was negatively correlated with symptom clusters, with higher activity levels corresponding to lower symptom burden. It is recommended to design personalized exercise prescriptions, health education, and exercise guidance based on patients’ activity levels and symptom load, aiming to increase physical activity and alleviate symptom burden.

Key words: Lung neoplasms, Physical therapy modalities, Exercise, Rehabilitation nursing

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