结核与肺部疾病杂志 ›› 2024, Vol. 5 ›› Issue (4): 345-351.doi: 10.19983/j.issn.2096-8493.2024045

• 综述 • 上一篇    下一篇

结核病与COVID-19相互作用的研究进展

何繁漪, 陆霓虹, 杜映荣()   

  1. 昆明市第三人民医院,昆明 650041
  • 收稿日期:2024-03-12 出版日期:2024-08-20 发布日期:2024-08-13
  • 通信作者: 杜映荣 E-mail:dyr_km@163.com
  • 基金资助:
    云南省科技厅重点研发计划社会发展专项(202303AC100026)

Research progress on the interaction between tuberculosis and COVID-19

He Fanyi, Lu Nihong, Du Yingrong()   

  1. The Third People’s Hospital of Kunming, Kunming 650041, China
  • Received:2024-03-12 Online:2024-08-20 Published:2024-08-13
  • Contact: Du Yingrong E-mail:dyr_km@163.com
  • Supported by:
    Yunnan Provincial Department of Science and Technology, Key Research and Development Plan, Social Development Special Project(202303AC100026)

摘要:

在新型冠状病毒感染(corona virus disease-2019, COVID-19)流行之前,结核病(tuberculosis,TB)是威胁公共健康的主要呼吸道传染病之一。两病具有共同的致病途径,都是主要经呼吸道飞沫传播,且临床特征相似,合并感染会造成双重负担,既可加重COVID-19的严重程度,又可恶化活动性TB,甚至引起细胞因子风暴,导致严重的呼吸系统疾病,增加患者的死亡风险。COVID-19大流行也对公共医疗保健系统提出了严峻的挑战,明显干扰了TB患者的医疗服务,进一步加大了全球TB患者的发病率和病亡率。因此,作者对COVID-19与TB两种传染病之间相互作用的研究进展进行综述,以期为临床研究和诊治提供参考。

关键词: 结核, 冠状病毒感染, 共病现象, 综述文献(主题)

Abstract:

Tuberculosis (TB) was one of the major respiratory infectious diseases threatening public health before the corona virus disease-2019 (COVID-19) pandemic. TB and COVID-19 have a common pathogenic pathway, mainly transmitted through respiratory droplets, and their clinical characteristics were similar. Co-infection of the two infectious diseases can cause a double burden, which not only aggravating the severity of COVID-19, but also worsening active TB, and even causing cytokine storms, leading to severe respiratory diseases and increasing the risk of death of patients. The COVID-19 pandemic also posed a serious challenge to the public health care system, significantly interfering with the health care services provided for TB patients, and further increasing the incidence and mortality of TB patients globally. Therefore, the authors provides a review of the research progress on the interactions between COVID-19 and TB, with the aim of providing reference for clinical research, diagnosis and treatment.

Key words: Tuberculosis, Coronavirus infections, Comorbidity, Review literature as topic

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